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Related Concept Videos

Disorders of the Urinary System01:20

Disorders of the Urinary System

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The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
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Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
13
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

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AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
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Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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Updated: Jul 11, 2025

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

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Published on: December 1, 2013

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Young population bladder neoplasms.

K Çivi Çetin1, S Öner, B Erdoğan

  • 1Department of Pathology, Eskisehir City Hospital, Eskisehir, Turkey. kismet.civicetin@sbu.edu.tr.

European Review for Medical and Pharmacological Sciences
|November 17, 2023
PubMed
Summary
This summary is machine-generated.

Bladder cancer is rare in individuals under 40. Young patients typically present with low-grade, low-stage urothelial carcinoma, showing excellent prognosis and minimal recurrence, supporting transurethral excision as a treatment.

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Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Bladder urothelial carcinoma is uncommon in patients under 40.
  • Limited data exists on the prognosis and clinical behavior of bladder cancer in younger individuals.
  • This study investigates bladder tumors in patients under 40.

Purpose of the Study:

  • To analyze the clinicopathological features of bladder tumors in patients under 40.
  • To compare the prognosis and clinical behavior of bladder cancer in young versus older patients.
  • To identify optimal treatment strategies for urothelial carcinoma in young adults.

Main Methods:

  • Retrospective analysis of patients diagnosed with urothelial neoplasia undergoing bladder surgery (2008-2020).
  • Inclusion of data on stage, grade, multifocality, smoking, recurrence, and survival.
  • Comparison of clinical and pathological features between patients under 40 (Group 1) and over 40 (Group 2).

Main Results:

  • 17 patients under 40 (average age 30.6) were identified with predominantly low-grade, low-stage tumors (pTa, papillomas).
  • Young patients exhibited single, small tumors with no progression and no recurrences.
  • Older patients showed higher rates of recurrence (7/10) and tumor progression (16.4%).

Conclusions:

  • Bladder urothelial cancer in patients under 40 is typically low-grade and low-stage.
  • Younger patients generally experience a favorable prognosis with infrequent recurrence.
  • Transurethral excision is recommended as the preferred treatment for bladder tumors in this demographic.