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Research progress on ginger polysaccharides: extraction, purification and structure-bioactivity relationship.

Yuan Wu1, Bing-Hang Li1, Miao-Miao Chen1

  • 1Engineering Research Center of Active Substance and Biotechnology, Ministry of Education, College of Chemistry, Chongqing Normal University, Chongqing, 401331, PR China. lbjll@hotmail.com.

Food & Function
|November 17, 2023
PubMed
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Ginger polysaccharides (GPs) show diverse bioactivities, including antioxidant and antitumour effects. Further research is needed to fully understand the structure-bioactivity relationship of these compounds for future applications.

Area of Science:

  • Phytochemistry
  • Pharmacology
  • Biochemistry

Background:

  • Ginger (Zingiber officinale) is a globally utilized source of herbal medicine and culinary spice.
  • Ginger polysaccharides (GPs) are key bioactive components with significant therapeutic potential.
  • Existing research highlights GPs' antioxidant, antitumour, anti-inflammatory, and immunomodulatory properties.

Purpose of the Study:

  • To comprehensively review current scientific literature on ginger polysaccharides (GPs).
  • To examine the extraction, purification, structure, and bioactivity of GPs.
  • To explore the critical structure-bioactivity relationship of GPs and their applications.

Main Methods:

  • Systematic literature search of published studies on ginger polysaccharides.

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  • Analysis of reported extraction and purification techniques for GPs.
  • Compilation and synthesis of data on GP structure, bioactivity, and applications.

    • Main Results:

    • GPs exhibit a wide range of bioactivities, including antioxidant, antitumour, anti-inflammatory, immunomodulatory, hypoglycaemic, and anticoagulant effects.
    • The structural characteristics of GPs are closely linked to their observed bioactivities.
    • Current research provides a foundation, but a comprehensive understanding of the structure-bioactivity relationship is still developing.

    Conclusions:

    • Ginger polysaccharides are promising compounds with diverse pharmacological effects.
    • Further investigation into the structure-bioactivity relationship of GPs is crucial for optimizing their therapeutic applications.
    • This review serves as a valuable reference for future research and development in the field of ginger polysaccharides.