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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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Exercise for chronic kidney disease: effects on vascular and cardiopulmonary function
Danielle L Kirkman1, Domenico A Chavez1
1Department of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, Virginia, United States.
American Journal of Physiology. Heart and Circulatory Physiology
|November 17, 2023
Summary
Exercise can improve vascular and cardiopulmonary function in patients with chronic kidney disease (CKD). This lifestyle strategy is crucial for managing cardiovascular disease (CVD) risk in CKD patients.
Area of Science:
- Nephrology
- Cardiology
- Exercise Physiology
Background:
- Patients with chronic kidney disease (CKD) exhibit high rates of cardiovascular disease (CVD).
- Vascular dysfunction and low cardiorespiratory fitness are key contributors to CVD in CKD.
- Current pharmacological treatments have limited success in reducing CVD prevalence in CKD.
Purpose of the Study:
- To review the effects of exercise on vascular and cardiopulmonary function in CKD patients.
- To highlight exercise as a therapeutic target for vascular dysfunction in CKD.
- To discuss future research directions for exercise interventions in CKD.
Main Methods:
- This is a narrative review.
- Literature search on exercise effects in CKD patients.
- Discussion of physiological mechanisms and clinical implications.
Main Results:
- Exercise positively impacts endothelial function and arterial stiffness in CKD.
- Physical activity improves cardiorespiratory fitness in individuals with CKD.
- Exercise offers a promising adjuvant strategy to pharmacological therapies for CVD risk reduction in CKD.
Conclusions:
- Exercise training is a vital lifestyle intervention for improving cardiovascular health in CKD.
- Targeting vascular dysfunction through exercise is a key strategy for managing CVD in CKD.
- Integrating exercise into routine clinical care is essential for CKD patients.
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