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Updated: Jul 11, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Visible light-mediated halogenation of organic compounds
Alexey A Festa1, Olga A Storozhenko1, Leonid G Voskressensky1
1Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya st. 6, Moscow, 117198, Russian Federation. erik.vandereycken@kuleuven.be.
Abstract:
The use of visible light and photoredox catalysis emerged as a powerful and sustainable tool for organic synthesis, showing high value for distinctly different ways of bond creation. Halogenated compounds are the cornerstone of contemporary organic synthesis: it is almost impossible to develop a route towards a pharmaceutical reagent, agrochemical, natural product, etc. without the involvement of halogen-containing intermediates. Moreover, the halogenated derivatives as final products became indispensable for drug discovery and materials science. The idea of this review is to understand and summarise the impact of visible light-promoted chemistry on halogenation and halofunctionalisation reactions.
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