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Allogenic Umbilical Cord Tissue for Rotator Cuff Injuries
Adarsh Aratikatla1, Justin Sidhu1, Nicola Maffulli2,3,4,5
1The Royal College of Surgeons in Ireland, Dublin, Ireland.
Sports Medicine and Arthroscopy Review
|November 17, 2023
Summary
Umbilical cord (UC) tissue and its stem cells show promise for treating rotator cuff injuries (RCIs). While safe and potentially effective, more research is needed to confirm benefits for shoulder repair.
Area of Science:
- Regenerative Medicine
- Orthopedics
- Biomaterials Science
Background:
- Rotator cuff injuries (RCIs) are common, impacting shoulder stability and mobility.
- Current treatments often involve surgery, which has limitations.
- Biological therapies offer a promising alternative for RCI management.
Conclusions:
- UC tissue and UC-derived mesenchymal stem cells represent a viable regenerative option for RCIs.
- Further adequately powered randomized controlled trials are necessary.
- More research is warranted to establish definitive efficacy and guide clinical application.

