Change in frequency of radiation induced micronuclei during interphase of four-cell mouse embryos in vitro

Two-cell mouse embryos were X-irradiated (2 Gy) in vitro. Comparison of the frequency of micronuclei in the early interphase of the four-cell stage with that in the late interphase revealed a small, but significant loss of micronuclei during interphase: 27.9 versus 23.4 micronuclei per 100 cells.