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Getting PrEP to the patients who need it.

Andrew V A Foley1, Daniel F Farrell2, Patricia Carr Reese3

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Many eligible individuals do not receive pre-exposure prophylaxis (PrEP) prescriptions for HIV prevention. Updated guidelines and new drug options can help close this gap in care.

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Area of Science:

  • Public Health
  • Infectious Disease Prevention
  • HIV/AIDS Research

Background:

  • Pre-exposure prophylaxis (PrEP) is a highly effective biomedical intervention for preventing HIV infection.
  • Current uptake of PrEP among eligible populations remains suboptimal, indicating a significant gap between need and access.
  • Factors contributing to low PrEP uptake include awareness, accessibility, and adherence challenges.

Purpose of the Study:

  • To highlight the disparity between PrEP eligibility and prescription rates for HIV prevention.
  • To discuss the potential impact of newer drug regimens and updated clinical recommendations on increasing PrEP access.
  • To identify strategies for reducing the gap in PrEP utilization.

Main Methods:

  • Review of current clinical guidelines and recommendations for PrEP.
  • Analysis of available data on PrEP eligibility and prescription trends.
  • Examination of emerging pharmacological options for PrEP therapy.

Main Results:

  • A significant proportion of individuals eligible for PrEP are not currently receiving prescriptions.
  • Newer PrEP drug regimens offer improved efficacy, tolerability, and dosing options.
  • Updated clinical recommendations provide expanded criteria for PrEP eligibility and usage.

Conclusions:

  • Closing the PrEP gap requires leveraging advancements in pharmacotherapy and updated clinical guidance.
  • Implementing evidence-based strategies is crucial to increase PrEP uptake and reduce HIV transmission.
  • Addressing systemic barriers to PrEP access is essential for maximizing its public health impact.