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Preventing RSV in children and adults: A vaccine update

Doug Campos-Outcalt1

  • 1University of Arizona, Phoenix.

The Journal of Family Practice
|November 17, 2023
PubMed

Insights

New vaccines and a monoclonal antibody offer protection against respiratory syncytial virus (RSV) for all age groups. Learn about their use in infants, children, adults, and during pregnancy.

Area of Science:

  • Immunology
  • Pediatrics
  • Public Health

Background:

  • Respiratory syncytial virus (RSV) is a common respiratory pathogen causing significant morbidity and mortality worldwide.
  • Existing preventive measures for RSV are limited, highlighting the need for novel interventions.

Purpose of the Study:

  • To review the available preventive strategies against RSV, including newly approved vaccines and a monoclonal antibody.
  • To elucidate the recommended usage of these interventions across different demographic groups.

Main Methods:

  • Literature review of clinical trials and guidelines regarding RSV prevention.
  • Synthesis of data on vaccine efficacy, safety, and monoclonal antibody administration.

Main Results:

  • Three distinct vaccines are now available for specific populations.
  • A new monoclonal antibody provides passive immunity against RSV infection.
  • Recommendations cover use in infants, children, adults, and pregnant individuals for optimal protection.

Conclusions:

  • Multiple options now exist for RSV prevention, significantly expanding public health capabilities.
  • Targeted application of vaccines and monoclonal antibodies can reduce the burden of RSV disease across the lifespan.

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