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Social vulnerability and lung malignancy mortality.

Ramzi Ibrahim1, Lewjain Sakr2, Jennifer A Lewis3

  • 1Department of Medicine, University of Arizona - Banner University Medical Center, Tucson, AZ, USA.

Journal of Cancer Policy
|November 17, 2023
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Summary
This summary is machine-generated.

Social vulnerability significantly impacts lung cancer mortality, especially in males and certain ethnic groups. Interventions targeting vulnerable populations are crucial for improving lung cancer outcomes.

Keywords:
DisparitiesEpidemiologicalLung cancerMortalitySocial vulnerability index

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Area of Science:

  • Public Health
  • Epidemiology
  • Social Determinants of Health

Background:

  • Lung cancer is a leading cause of death in the U.S.
  • Social determinants of health (SDOH) influence lung cancer treatment and prognosis.
  • The Social Vulnerability Index (SVI) quantifies SDOH.

Purpose of the Study:

  • To investigate the impact of the SVI on lung cancer mortality.
  • To utilize descriptive epidemiology to analyze SVI and lung cancer death rates.

Main Methods:

  • Used CDC mortality data (2014-2018) for lung malignancies.
  • Obtained SVI data from CDC Agency for Toxic Substances and Disease Registry.
  • Calculated age-adjusted mortality rates (AAMR) for SVI quartiles and demographic subgroups.

Main Results:

  • Counties with the highest SVI (SVI-Q4) showed higher cumulative AAMR (4.48 excess deaths/100,000 person-years) than the least vulnerable (SVI-Q1).
  • Males in SVI-Q4 had significantly higher AAMR (9.96 excess deaths/100,000 person-years) compared to SVI-Q1; no difference in females.
  • Higher AAMR in SVI-Q4 observed across Hispanic and non-Hispanic populations, excluding American Indian/Alaska Native groups. Trends held for metropolitan and non-metropolitan areas.

Conclusions:

  • The SVI is a significant factor in lung cancer mortality.
  • Interventions targeting socially vulnerable populations are needed to reduce lung cancer deaths.
  • Addressing SDOH is critical for improving lung cancer prognosis.