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Updated: Aug 5, 2026

Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo
Published on: May 9, 2016
Studies on heparin immobilization to collagen
Abstract:
After activation of carboxyl groups with carbodiimide, heparin binds to collagen by a stable covalent linkage. Covalent binding of heparin to collagen results in enhanced stability of the preparation. Also, heparin bound collagen retains its anticoagulative activity.
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