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Updated: Jul 10, 2025

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APS calculator: a data-driven tool for setting outcome-based analytical performance specifications for measurement

Hikmet Can Çubukçu1,2, Florent Vanstapel3,4, Marc Thelen5,6

  • 1General Directorate of Health Services, Rare Diseases Department, Turkish Ministry of Health, Ankara, Türkiye.

Clinical Chemistry and Laboratory Medicine
|November 18, 2023
PubMed
Summary

Laboratory professionals can now calculate analytical performance specifications (APS) for measurement uncertainty (MU) using a new web application. This tool simulates the impact of MU on patient care outcomes based on user-defined limits and population data.

Keywords:
ISO 15189analytical performance specificationsdatadecision limitsmeasurement uncertaintyoutcome

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