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![Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F55858.jpg&w=3840&q=50)
Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase
Published on: December 4, 2017
Iron(III) Complexes with Hydrogen Peroxide which Can Discriminate Two Reaction Types; Oxidation (H-Atom Abstraction)
1epartment of Chemistry, Faculty of Science, Yam agata University, Yamagata 990, Japan.
Abstract:
Iron(III)-NTA (nitrilotriacetic acid) solution shows high activity for oxidative degradation of 2'-deoxyribose in the presence of hydrogen peroxide, whereas its activity of Fe(III)-TFDA (2-aminomethyltetrahydrofuran-N,N-diacetic acid) is negligible under the same experimental conditions; however the latter solution exhibits abnormally higher reactivity for oxygenation reaction at 8-position of 2'-deoxyguanosine than other iron(III) chelates examined. These results suggest that oxidative degradation of deoxyribose and the oxygenation of deoxyguanosine are caused by a different iron(III)-peroxide species.
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