Cardiovascular consequences of financial stress: A systematic review and meta-analysis
Shiba Sai Swarup1, Asha K P2, Bijaya Kumar Padhi3
1Department of Community Medicine, District Headquarter Hospital, Koraput, India.
Insights
Financial stress is linked to increased risk of major cardiac outcomes like coronary artery disease (CAD) and coronary heart disease (CHD). This review highlights the need for standardized financial stress measures in patient care to improve cardiovascular health.
Area of Science:
- Cardiology
- Public Health
- Health Economics
Background:
- Cardiovascular diseases (CVD), including coronary artery disease (CAD) and coronary heart disease (CHD), are leading causes of death globally.
- Financial stress is an emerging non-traditional risk factor for CVD.
- This study systematically reviews the association between financial stress and major cardiac events.
Approach:
- A comprehensive literature search was performed across multiple databases up to September 20, 2023.
- Seven primary studies met the inclusion criteria, assessing financial stress and the incidence of CAD, CHD, or major cardiovascular outcomes.
- Study quality was assessed using the Newcastle-Ottawa Scale, and data were analyzed using a random-effects model in R version 4.3.
Key Points:
- Seven studies involving diverse populations found a significant association between financial stress and major cardiac outcomes.
- A combined hazard ratio (HR) of 1.191 (95% CI: 1.00 to 1.47) indicated an increased risk.
- Potential publication bias and variability in financial stress definitions were noted.
Conclusions:
- Evidence supports a link between financial stress and the incidence of CAD/CHD and major cardiac outcomes.
- Standardized definitions and measurement tools for financial stress are urgently needed.
- Integrating financial stress assessment into patient care and health policies can improve cardiovascular health and well-being.
Background:
Cardiovascular diseases (CVD), notably coronary artery disease (CAD) and coronary heart disease (CHD), are predominant contributors to global morbidity and mortality. Financial stress is recognized as a non-traditional risk factor for CVD. The objective of this study is to conduct a systematic review and meta-analysis on the association between financial stress and the incidence of major cardiac outcomes.
Methods:
A literature search was conducted across multiple databases up until September 20, 2023. Primary studies reporting the association between financial stress and the incidence of CAD, CHD, or major cardiovascular outcomes were included. The quality of the incorporated studies was evaluated using the Newcastle-Ottawa Scale. Statistical analysis was performed using R version 4.3, employing a random-effects model.
Results:
Out of 2,740 identified studies, seven satisfied the inclusion criteria, displaying a diverse range in design, settings, and participant demographics. A significant association was found between financial stress and major cardiac outcomes, with a combined hazard ratio (HR) of 1.191 (95% CI: 1.00 to 1.47), p<0.001 from five studies. Possible publication bias and variations in definitions and measurements of financial stress were noted among the studies.
Conclusion:
The available literature substantiates an association between financial stress and the incidence of CAD/CHD or major cardiac outcomes, underscoring an urgent need for standardized definitions and measurements of financial stress. Our findings support the integration of financial stress assessments in patient care and the development of health policies emphasizing economic strains to enhance cardiovascular health outcomes and overall well-being.
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