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Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
Predictors for achieving optimal sleep in healthy children: Exploring sleep patterns in a sleep extension trial
Barbara C Galland1, Jillian J Haszard2, Rosie Jackson3
1Department of Women's & Children's Health, University of Otago, Dunedin, New Zealand.
Insights
Children with shorter sleep durations benefit most from earlier bedtimes. A baseline sleep period under 8.5 hours predicted significant sleep gains, experimentally validating earlier bedtimes for improved sleep in children.
Area of Science:
- Pediatric Sleep Medicine
- Chronobiology
- Behavioral Sleep Science
Background:
- Earlier bedtimes can increase sleep duration in children.
- Predictors of successful earlier bedtime interventions are not well understood.
- This study investigates individual sleep characteristics influencing response to earlier bedtimes.
Purpose of the Study:
- To identify which children benefit most from earlier bedtimes.
- To determine which sleep pattern features predict successful sleep extension.
- To experimentally validate the impact of earlier bedtimes on children's sleep.
Main Methods:
- A randomized crossover trial involving 99 children (aged 8-12 years) with no prior sleep disturbances.
- Sleep was monitored using actigraphy during baseline and intervention weeks (earlier or later bedtime).
- Statistical analyses (linear/logistic regression) identified predictors of sleep gain from earlier bedtimes.
Main Results:
- Children with less total sleep time and shorter sleep periods at baseline gained the most sleep from earlier bedtimes.
- A baseline sleep period of <8 hours 28 minutes was optimal for predicting successful sleep extension (>30 minutes).
- Lower sleep efficiency and more variable sleep timing also predicted greater sleep gains.
Conclusions:
- Children with shorter baseline sleep periods (<8.5 hours) showed the greatest improvement in sleep duration with earlier bedtimes.
- Earlier bedtimes are experimentally validated as an effective strategy to increase sleep in specific pediatric populations.
- Identifying children with shorter sleep durations can optimize earlier bedtime interventions.
Study Objectives:
Earlier bedtimes can help some children get more sleep, but we don't know which children, or what features of their usual sleep patterns could predict success with this approach. Using data from a randomized crossover trial of sleep manipulation, we sought to determine this.
Methods:
Participants were 99 children aged 8-12years (49.5% female) with no sleep disturbances. Sleep was measured by actigraphy at baseline and over a restriction or extension week (1 hour later or earlier bedtime respectively), randomly allocated and separated by a washout week. Data were compared between baseline (week 1) and extension weeks only (week 3 or 5), using linear or logistic regression analyses as appropriate, controlling for randomization order.
Results:
One hour less total sleep time than average at baseline predicted 29.7 minutes (95% CI: 19.4, 40.1) of sleep gained and 3.45 (95% CI: 1.74, 6.81) times higher odds of successfully extending sleep by >30 minutes. Per standardized variable, less total sleep time and a shorter sleep period time were the strongest predictors (significant odds ratios (ORs) of 2.51 and 2.28, respectively). Later sleep offset, more variability in sleep timing and lower sleep efficiency also predicted sleep gains. The sleep period time cut-point that optimized prediction of successful sleep gains was <8 hours 28 minutes with 75% of children's baseline sleep in that range.
Conclusions:
Children with a baseline sleep period time <8½ hours a night obtained the most sleep from earlier bedtimes maintained over a week, demonstrating experimentally the value of earlier bedtimes to improve sleep.
Clinical Trials Registry:
Australian New Zealand Clinical Trial Registry, ACTRN12618001671257, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367587&isReview=true.
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