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Updated: Jul 10, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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[Update on targeted biopharmaceuticals in systemic sclerosis!]

B Chaigne1, L Mouthon1

  • 1Service de médecine interne, centre de référence maladies autoimmunes systémiques Rares d'Ile de France, hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; AP-HP-CUP, Université Paris Cité, Hôpital Cochin, 75014 Paris, France.

La Revue De Medecine Interne
|November 18, 2023
PubMed

Insights

Systemic sclerosis (SSc) clinical trials are advancing, with recent studies focusing on endpoint criteria. Future trials are also being planned for this rare autoimmune disease.

Area of Science:

  • Rheumatology
  • Immunology
  • Fibrosis Research

Context:

  • Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease.
  • Characterized by inflammation, fibrosis, and autoimmunity.
  • SSc research has seen increased clinical trial activity in the last decade.

Purpose:

  • To review SSc clinical trial results published in the last five years.
  • To analyze trials based on chosen endpoint criteria.
  • To outline ongoing and upcoming SSc clinical trials.

Summary:

  • Presents results from SSc clinical trials over the past five years, categorized by endpoint criteria.
  • Details ongoing and anticipated clinical trials for systemic sclerosis.
  • Highlights the growing research interest and therapeutic development in SSc.

Impact:

  • Provides a comprehensive overview of recent SSc trial outcomes.
  • Informs future research directions and trial design in systemic sclerosis.
  • Contributes to the understanding of therapeutic advancements for SSc patients.
Keywords:
FibroseFibrosisInterstitial lung diseasePneumopathie interstitielle diffuseRaynaudRaynaud's phenomenonSclérodermie systémiqueSystemic sclerosisTraitement

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