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Updated: Jul 10, 2025
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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
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Factors Associated with Respiratory Health and Function in Duchenne Muscular Dystrophy: A Systematic Review and
E Landfeldt1, A Aleman2,3, S Abner4
1IQVIA, Stockholm, Sweden.
Journal of Neuromuscular Diseases
|November 19, 2023
Summary
Respiratory issues significantly impact Duchenne muscular dystrophy (DMD) patients. This review identifies 10 key factors, including genetics and treatments, affecting respiratory health in DMD, guiding future research and care.
Area of Science:
- Neurology
- Pulmonology
- Genetics
Background:
- Respiratory complications are a major cause of morbidity and mortality in Duchenne muscular dystrophy (DMD).
- Despite medical advances, understanding factors influencing respiratory health in DMD remains critical for patient outcomes.
Conclusions:
- Ten factors, including genetics, therapies, and clinical characteristics, are associated with respiratory health in DMD.
- Further research is needed on genotype-phenotype correlations and real-world impacts of new DMD therapies.
- Findings aim to inform clinical practice and guide future research for the DMD population.
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