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Updated: Jul 10, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
Published on: June 9, 2023
Design and performance of pH-responsive cyano-Raman label SERS probes based on single urchin Au nanoparticles
Yang Zhou1, Zejie Yu1, Qirong Zhou1
1State Key Laboratory of Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Nanjing University of Posts & Telecommunications, Nanjing 210023, China. iamlzhang@njupt.edu.cn.
Abstract:
A cyano-Raman label pH-responsive SERS probe was constructed by immobilizing 6-MPN molecules onto the surface of a single urchin Au nanoparticle (AuNP). The effects of different conditions on the synthetic materials were investigated and the optical properties of the single nanoparticles were evaluated. The peak-strength ratio of SERS probes at 1589 cm-1 and 2240 cm-1 exhibited a linear relationship in the pH range 4-7. The properties and stability of the probe were also verified by the acid-base cycle and ion interference tests.
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