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Successful T replete haploidentical HSCT with post-transplant cyclophosphamide in two patients with Wiskott-Aldrich

Rajan Kapoor1, Uday Yanamandra2, Rajiv Kumar3

  • 1Professor & Head (Hematology), Army Hospital (Research & Referral), Delhi Cantt, India.

Medical Journal, Armed Forces India
|November 20, 2023
PubMed

We describe two young patients with Wiskott-Aldrich Syndrome (WAS) who were treated by T-replete hematopoietic stem cell transplantation (HSCT) from the HLA haploidentical father according to a modified Baltimore protocol. Whereas similar protocols have been successfully used in various malignant and non-malignant diseases, this is the first report for this particular disease. The data being presented pertains to the report about two successful haploidentical transplants with post transplant cyclophosphamide (PTCY) after busulfan-based conditioning.

Keywords:
HaploidenticalPost-transplant cyclophosphamideT-repleteWiskott-Aldrich syndrome

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