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Updated: Jul 10, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
Changing perspectives: unveiling the risks of ashwagandha-induced hepatotoxicity
Sergio Casiano-Manzano1, Macarena Torres-Larrubia1, Alberto Masa-Caballero2
1Gastroenterology , Hospital Universitario de Cáceres.
Abstract:
Ashwagandha, an herb popular in Ayurvedic medicine, is renowned for its health-enhancing properties. However, its association with liver damage in recent years has raised significant concerns, necessitating careful assessment and management. This case underscores the dangers of Ashwagandha, particularly for individuals with preexisting liver conditions, where it can lead to life-threatening acute-on-chronic liver failure. The lack of solid clinical evidence supporting Ashwagandha's health claims emphasizes the need for an evidence-based approach. Public education is essential to raise awareness of the risks associated with herbal supplements and prevent liver diseases.
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