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Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance

Wolfgang von Scheidt1,2, Bruno Reichart3, Bruno Meiser4

  • 1I.Medizinische Klinik, University Hospital Augsburg, University of Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany. w.scheidt@med1-klinikum-augsburg.de.

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
|November 20, 2023
PubMed

Insights

This study reports a unique case of 40-year survival following heart transplantation. The patient maintained normal graft function and achieved spontaneous operational tolerance, a rare outcome in transplant recipients.

Area of Science:

  • Cardiology
  • Immunology
  • Transplantation Science

Background:

  • Heart transplantation is a life-saving procedure for end-stage heart failure.
  • Long-term graft survival and the development of operational tolerance remain significant challenges in transplantation.
  • Understanding factors contributing to exceptional long-term outcomes is crucial for advancing transplant medicine.

Keywords:
Cardiac allograft vasculopathyHeart transplantationImmunosuppressionLong-term survivalMyocardial functionTolerance

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