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[Typhoid fever in childhood]

S P Geelen, J J Roord, A Fleer

    Tijdschrift Voor Kindergeneeskunde
    |October 1, 1986
    PubMed

    Insights

    Typhoid fever is rare in the Netherlands, often acquired during travel to endemic regions. Diagnosis relies on cultures, with bone marrow culture being most effective, and chloramphenicol remains the primary treatment.

    Area of Science:

    • Infectious Diseases
    • Pediatrics
    • Microbiology

    Background:

    • Typhoid fever is uncommon in the Netherlands, with most cases linked to international travel.
    • This study reviews three pediatric cases from 1985, including a complicated course of illness.

    Observation:

    • Case histories of three children admitted with suspected typhoid fever in 1985.
    • One child experienced a complicated disease progression.

    Findings:

    • Blood, feces, and bone marrow cultures are crucial for diagnosing typhoid fever.
    • Bone marrow culture is the most sensitive diagnostic method, particularly in children previously treated with antibiotics.
    • Chloramphenicol is identified as the drug of choice for treatment.

    Implications:

    • Highlights the importance of considering travel history in diagnosing uncommon infections.
    • Emphasizes optimal diagnostic methods and treatment for pediatric typhoid fever.
    • Recommends oral typhoid vaccination for children traveling to endemic areas.

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