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Updated: Jul 10, 2025

Sample Preparation for Computed Tomography-based Three-dimensional Visualization of Murine Hind-limb Vessels
Published on: October 7, 2021
Indications for computed tomography angiography in limb trauma
Wasim Awal1,2, Julia De Groot1,2
1Sunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.
Computed tomography angiograms (CTAs) for limb trauma are indicated by hard signs of vascular compromise or an arterial pressure index (API) <0.9. Soft signs may guide API testing, and CTAs are not routinely needed for knee dislocations.
Area of Science:
- Radiology
- Vascular Surgery
- Trauma Surgery
Background:
- Computed tomography angiograms (CTAs) are crucial for diagnosing vascular injury in limb trauma.
- Current guidelines lack consensus on CTA indications, leading to overuse and potential patient harm.
- Defining appropriate CTA indications in limb trauma is essential for optimizing patient care.
Purpose of the Study:
- To establish clear indications for utilizing CTAs in patients with limb trauma.
- To reduce unnecessary CTA utilization and associated risks.
- To correlate clinical findings with CTA-detected vascular injuries.
Main Methods:
- Retrospective cohort study of 49 consecutive CTAs performed between January and December 2022.
- Collected demographic and clinical data, including physical examination findings (hard and soft signs) and arterial pressure index (API).
- Analyzed correlations between clinical factors and CTA-confirmed vascular injuries.
Main Results:
- Vascular injury was detected in 10.2% of CTAs.
- Hard signs (e.g., absent pulse) and API <0.9 were significantly correlated with vascular injury (P < 0.001 and P = 0.02, respectively).
- API measurement showed 100% sensitivity and specificity; hard signs had 90% sensitivity and 82% specificity. Soft signs had 100% sensitivity but poor specificity. Knee dislocations were not associated with vascular injury (P = 0.5).
Conclusions:
- CTAs are indicated for limb trauma in hemodynamically stable patients with hard signs of vascular compromise or an API <0.9.
- Soft signs can help identify patients who would benefit from API measurement.
- Routine CTAs for knee dislocations may not be necessary.
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