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Acquired infundibular stenosis.

D R Bodner, A A Caldamone, M I Resnick

    Urology
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Acquired infundibular stenosis, a rare complication causing pancalyceal obstruction, was studied in six patients. These patients developed chronic urinary tract infections and reflux after urinary diversion, highlighting a distinct clinical syndrome.

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    Area of Science:

    • Nephrology
    • Urology
    • Surgical Pathology

    Background:

    • Acquired infundibular stenosis is an uncommon cause of pancalyceal obstruction.
    • This condition can arise secondary to urinary diversion procedures, leading to complications such as chronic infections and reflux.
    • Tuberculosis is a known cause, but this study focuses on non-tuberculous cases.

    Purpose of the Study:

    • To describe the clinical, radiographic, and pathological features of acquired infundibular stenosis in patients with ileal conduits.
    • To identify potential therapeutic guidelines for managing this rare condition.
    • To investigate the long-term outcomes of patients with acquired infundibular stenosis and ileal conduit urinary diversion.

    Main Methods:

    • Retrospective case series analysis of six patients with acquired infundibular stenosis.

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  • Review of clinical histories, radiographic imaging (e.g., CT scans, IVP), and pathological findings.
  • Assessment of urinary diversion via ileal conduits, ileal-ureteral reflux, and chronic urinary tract infections.
  • Main Results:

    • Six patients with acquired infundibular stenosis not associated with tuberculosis were identified.
    • All patients had undergone urinary diversion with ileal conduits for at least eleven years.
    • Documented findings included significant ileal-ureteral reflux and recurrent urinary tract infections.

    Conclusions:

    • Acquired infundibular stenosis is a distinct syndrome in patients with long-term ileal conduits, characterized by reflux and chronic infections.
    • The clinical presentation, imaging findings, and pathology are described to aid in diagnosis.
    • Therapeutic strategies should be considered to manage this complication and improve patient outcomes.