Advances in the treatment of hepatogenous diabetes: A review
Yanru Deng1, Keyu Li2, Ang Li2
1Department of Clinical Nutrition, West China Hospital; Sichuan University, Chengdu, Sichuan Province, China.
Insights
Hepatogenous diabetes (HD), a complication of chronic liver disease, has a poor prognosis and lacks a defined treatment. This review explores recent advancements to find effective HD management strategies.
Area of Science:
- Endocrinology and Metabolism
- Hepatology
Background:
- Hepatogenous diabetes (HD) is a metabolic disorder linked to chronic liver disease, particularly cirrhosis.
- Patients with HD face severe complications like gastrointestinal bleeding and hepatic encephalopathy.
- HD progression often mirrors cirrhosis advancement, increasing mortality and liver cancer risk.
Conclusions:
- Effective treatment strategies for hepatogenous diabetes are critically needed.
- Further research and clinical trials are essential to develop a systematic approach to HD management.
- Improving HD treatment could significantly enhance patient outcomes and reduce mortality.
Abstract:
Hepatogenous diabetes (HD) is a glycogen metabolism disorder that arises as a consequence of chronic liver disease. The condition is frequently detected in patients diagnosed with cirrhosis, which is a result of advanced liver disease. The prognosis for patients with HD is generally poor, and they are at a heightened risk for serious complications such as gastrointestinal bleeding, primary peritonitis, and hepatic encephalopathy. Hepatogenous diabetes progression is often associated with cirrhosis progression, which leads to the development of liver cancer and increased patient mortality. Despite the prevalence and severity of HD, no systematic treatment strategy for clinical management of the condition has been proposed by any research or institutions to date. This paper conducts an extensive review of recent advancements in HD treatment in the quest for an effective treatment approach that may improve the overall prognosis of HD.
More Related Videos
Related Concept Videos
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Oral Hypoglycemic Agents: Biguanides and Glitazones
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...


