Related Experiment Video
Updated: Jul 10, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endogenous endophthalmitis caused by urinary tract infection: A case report
Cong Ren1,2,3, Zhongen Li1, Fan Meng1,4
1Shandong University of Traditional Chinese Medicine, Jinan, China.
Rationale:
Endogenous endophthalmitis is a vision-threatening intraocular infection caused by hematogenous spread of infectious organisms from distant sites.
Patient Concerns:
A 71-year-old man with a history of fever and dysuria 5 days prior to presentation presented with sudden loss of vision in his left eye. The patient had no history of ocular surgery or trauma, and ocular examination revealed a large amount of exudative plaque covering the pupil. Therefore, fundus examination was not feasible. B-scan ultrasonography revealed a dome-shaped subretinal mass with an exudative retinal detachment.
Diagnosis:
Endogenous endophthalmitis was diagnosed on the basis of these findings.
Interventions:
The patient underwent pars plana vitrectomy and the early postoperative course was favorable.
Outcomes:
Vitreous cultures grew gram-negative bacilli, identified as Klebsiella pneumonia. Urinalysis revealed white blood cells (++) and urinary tract infection was the only identifiable risk factor for endogenous endophthalmitis.
Lessons:
Urinary tract infection is an independent risk factor for endogenous endophthalmitis.
More Related Videos
08:53Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
07:34Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis
Published on: April 16, 2019
Related Concept Videos
Glaucoma: Overview
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...