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[Clinico-biochemical and morphological changes in obstructive calculous pyelonephritis in children]
Vestnik Khirurgii Imeni I. I. Grekova
|October 1, 1986
Summary
Obstructive calculous pyelonephritis causes significant biochemical changes, including elevated enzyme activity and lipid levels. Surgical intervention impacts these clinico-biochemical and kidney alterations.
Area of Science:
- Nephrology
- Urology
- Biochemistry
Background:
- Obstructive calculous pyelonephritis is a complex kidney condition.
- Understanding its clinico-biochemical and morphological impact is crucial for patient management.
Purpose of the Study:
- To comparatively analyze clinico-biochemical and morphological changes in patients with obstructive calculous pyelonephritis.
- To evaluate the effects of surgical treatment on these alterations.
Main Methods:
- Study involved 38 patients diagnosed with obstructive calculous pyelonephritis.
- Comparative analysis of biochemical markers and kidney morphology before and after surgical intervention.
Main Results:
- Significantly elevated lactate dehydrogenase (LDG) and other enzyme activities were observed.
- Increased levels of cholesterol and total phospholipids were noted.
- Histomorphological alterations in the kidney correlated with biochemical findings.
Conclusions:
- Obstructive calculous pyelonephritis is associated with distinct biochemical and morphological kidney changes.
- Surgical treatment influences these observed alterations, warranting further investigation into recovery patterns.