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Updated: Jul 28, 2026
![Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62334.jpg&w=3840&q=50)
Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
Published on: February 17, 2022
Composite Angioimmunoblastic T-Cell Lymphoma and Diffuse Large B-Cell Lymphoma Presenting with Distributive Shock
Nisha Hariharan1, Alisha Kabadi2, Michelle Don3
1Department of Medicine, Division of Hematology/Oncology, University of California, La Jolla, CA 92093, USA.
Composite lymphoma, a rare simultaneous occurrence of angioimmunoblastic T-cell lymphoma (AITL) and diffuse large B-cell lymphoma (DLBCL), can present with distributive shock. This case study details successful treatment with brentuximab vedotin and rituximab, resolving shock.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Composite lymphoma involving angioimmunoblastic T-cell lymphoma (AITL) and diffuse large B-cell lymphoma (DLBCL) is exceptionally rare.
- Established treatment protocols for this rare condition are lacking.
- The simultaneous presentation of AITL and DLBCL can lead to complex clinical scenarios, including distributive shock.
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