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Asthildur Arnadottir1,2, Jakob Bønløkke3, Steffen Loft4

  • 1Forskningsenheden for Almen Praksis, Region Sjælland.

Ugeskrift for Laeger
|November 21, 2023
PubMed
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Environmental research·2025

Heatwaves are increasingly common and deadly. Greater preparedness and awareness are crucial, especially for those with chronic conditions or on medications affecting heat regulation.

Area of Science:

  • Environmental Health
  • Public Health
  • Clinical Medicine

Background:

  • Heatwaves represent a growing threat, recognized as the leading weather-related cause of mortality in high-income nations.
  • Excess mortality during heatwaves is largely preventable, underscoring the need for enhanced public health strategies and individual preparedness.
  • Existing non-communicable diseases and common medications can exacerbate health risks during extreme heat events.

Approach:

  • This review synthesizes current understanding of heatwave impacts on public health.
  • It examines the interplay between environmental conditions, pre-existing health status, and pharmacological interventions.
  • The review highlights evidence linking heat exposure to increased hospitalizations and mortality.

Key Points:

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  • Vulnerable populations, including those with chronic illnesses, face heightened risks during heatwaves.
  • Many frequently prescribed medications can interfere with the body's thermoregulation, potentially increasing heat-related morbidity and mortality.
  • There is a critical need for further research into the specific effects of prescribed medications on heatwave outcomes.

    • Conclusions:

    • Increased awareness and preparedness are essential to mitigate heatwave-related deaths.
    • Healthcare providers should consider medication effects on thermoregulation in patients during heat advisories.
    • Further investigation into medication-heatwave interactions is urgently required to inform clinical practice and public health policy.