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Updated: Jul 10, 2025

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
Ectopic adrenal tissue in a cat that underwent an ovariohysterectomy
Kristen Knight1, Helena Vogel2, Matthew Bischoff1
11VCA Animal Hospital, Aurora, IL.
Objective:
To describe the use of ultrasound and adrenal function testing to confirm that excised periovarian tissue is normal ectopic adrenal tissue (EAT).
Animal:
A 6-month-old female domestic shorthair cat.
Clinical Presentation, Progression, And Procedures:
The cat underwent an ovariohysterectomy procedure, during which abnormal tissue was discovered adjacent to both ovaries. The tissue was removed during the ovariohysterectomy and submitted for histopathology, which was consistent with adrenal gland tissue, initially raising concern for an inadvertent adrenalectomy. Abdominal ultrasound and an adrenal function test were performed that confirmed normal adrenal structure and function; thus, the removed structure was diagnosed as EAT.
Treatment And Outcome:
The patient continued to recover from the procedure uneventfully at home.
Clinical Relevance:
Parovarian nodules are an uncommon finding but when observed and biopsied, may be mistaken for physiologic adrenal tissue on the basis of histopathologic features alone without awareness of their existence and clinical context. The use of abdominal ultrasound and ACTH stimulation test offers an affirmative method of differentiating adrenal gland tissue from EAT.
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