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Published on: August 30, 2024
[Rheumatic cardiopathies and its risk factors: about 50 cases]
Ines Maaloul1, Nihed Bouzidi1, Roeya Kolsi1
1Service de pédiatrie, CHU Hédi Chaker. Sfax. Tunisie.
Insights
Acute rheumatic fever (ARF) in children frequently leads to cardiac involvement, with 44% of patients developing heart lesions. Key risk factors include age over 8, heart murmurs, and elevated CRP levels, highlighting the need for improved prevention.
Area of Science:
- Pediatrics
- Cardiology
- Rheumatology
Context:
- Acute rheumatic fever (ARF) is a significant multisystemic inflammatory disease.
- Cardiac involvement is the most severe manifestation of ARF.
- Understanding cardiac involvement and its risk factors in children is crucial for effective management.
Purpose:
- To analyze the prevalence and characteristics of cardiac involvement in children diagnosed with ARF.
- To identify risk factors associated with the development of cardiac lesions in pediatric ARF cases.
Summary:
- A retrospective study analyzed 50 children under 14 hospitalized for ARF over 12 years (2010-2022).
- Cardiac lesions were observed in 44% of patients, with valvular sequelae in 19.
- Risk factors identified included age > 8 years, heart murmur, prolonged PR interval, elevated CRP, and elevated VS.
Impact:
- Findings underscore ARF's continued status as a public health concern in Tunisia.
- Highlights the serious morbidity associated with ARF, particularly cardiac complications.
- Emphasizes the necessity of strengthening preventive strategies for ARF and its cardiac sequelae.
Introduction:
Acute rheumatic fever (ARF) is a multi-systemic disease, in which cardiac involvement is the most serious major manifestation of disease. The aim of this study was to analyse cardiac involvement in children with ARF and his risk factors.
Materials And Methods:
It were a retrospective study including all children under the age of 14 years who were hospitalized for ARF in the pediatric department of the CHU Hédi Chaker of Sfax, during a period of twelve years (2010-2022).
Results:
We collected 50 cases (31 boys and 19 girls). Twenty-two patients (44%) developed cardiac lesions. The mean age at diagnosis was 9.6 years [5-14 years]. A pathological heart murmur was detected in 14 cases (n = 14/22) was classified as mild carditis in 15 cases, moderate carditis in 5 cases and severe in 2 cases. The median follow-up time was 3,3 years. Nineteen patients developed valvular sequelae Risk factors of cardiac lesions was: age more than 8 years, heart murmur, allonged PR, CRP > 100 mg/l and VS > 100 mm.
Conclusion:
CR is still a public health problem in Tunisia. It is a serious pathology that can cause serious increases in morbidity rates. Thus, we must strengthen preventive strategies.
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