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Updated: Jul 10, 2025

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Published on: April 21, 2022
Malignant pleural effusion due to angiosarcoma: A rare entity
Ashley N Meerschaert1, Robert J DeCoste
1At Corewell Health William Beaumont University Hospital in Royal Oak, Mich., Ashley N. Meerschaert and Robert J. DeCoste III practice pulmonary and critical care medicine. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Angiosarcoma is a rare and aggressive vascular malignancy that typically originates in the skin or soft tissue of the body. It is known to have a propensity for metastasis to the lung parenchyma in the form of pulmonary nodules and cavitary lesions; however, a less commonly described entity is in the form of a malignant pleural effusion. Management of a malignant pleural effusion due to angiosarcoma presents a unique challenge. This article describes the challenges faced during one patient's diagnostic and treatment course, and the anticipated future complications of his aggressive disease.
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