Related Experiment Video
Updated: Jul 10, 2025
An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
Published on: November 30, 2022
In-hospital care of children with COVID-19
Oi-Wa Chan1, En-Pei Lee1, Cheng-Che Chou2
1Division of Pediatric Critical Care Medicine, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, Taiwan.
Insights
Children with underlying disorders can develop critical COVID-19 illness. This review details in-hospital care for pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, covering respiratory support, ECMO, and MIS-C.
Area of Science:
- Pediatric Infectious Diseases
- Critical Care Medicine
- Public Health
Background:
- While children generally experience milder COVID-19, those with pre-existing conditions are at risk for severe illness.
- Existing research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) predominantly focuses on adult patients.
- Understanding pediatric COVID-19 critical care is crucial for effective pandemic response.
Purpose of the Study:
- To provide an expert literature review on the in-hospital management of pediatric COVID-19.
- To consolidate knowledge on critical care interventions for children with SARS-CoV-2 infection.
- To address knowledge gaps concerning the management of severe pediatric COVID-19 cases.
Main Methods:
- Comprehensive review of existing literature on pediatric COVID-19 critical care.
- Synthesis of expert recommendations and clinical guidelines.
- Focus on key areas of in-hospital management for severe cases.
Main Results:
- Detailed review of respiratory support strategies, including mechanical ventilation and extracorporeal membrane oxygenation (ECMO).
- Discussion on the diagnosis and management of multisystem inflammatory syndrome in children (MIS-C).
- Overview of hemodynamic support, organ support, and pharmaceutical interventions (antivirals, anti-inflammatories, antithrombotics).
Conclusions:
- Effective management of pediatric COVID-19 requires a multidisciplinary approach.
- Specific considerations for respiratory failure, ECMO, MIS-C, and organ support are vital.
- Further research is needed to optimize treatment protocols for critically ill children with SARS-CoV-2 infection.
Abstract:
Children have been reported to be less affected and to have milder severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than adults during the coronavirus disease 2019 (COVID-19) pandemic. However, children, and particularly those with underlying disorders, are still likely to develop critical illnesses. In the case of SARS-CoV-2 infection, most previous studies have focused on adult patients. To aid in the knowledge of in-hospital care of children with COVID-19, this study presents an expert review of the literature, including the management of respiratory distress or failure, extracorporeal membrane oxygenation (ECMO), multisystem inflammatory syndrome in children (MIS-C), hemodynamic and other organ support, pharmaceutical therapies (anti-viral drugs, anti-inflammatory or antithrombotic therapies) and management of cardiopulmonary arrest.
More Related Videos
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
11:27A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
Related Concept Videos
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
01:30Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
00:59Hospitals-II
Nurses that work in...
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...