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COVID and COVID vaccine-related corneal morbidity: A review

Navneet Sidhu1, Murugesan Vanathi, Noopur Gupta

  • 1Dr. R. P. Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Ophthalmology
|November 22, 2023
PubMed

Insights

This review summarizes corneal complications from COVID-19 infection and vaccination, including corneal melts and graft issues. Understanding these ocular side effects aids clinical recognition and management.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Vaccinology

Background:

  • Systemic coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents with various ocular manifestations.
  • Adverse events following COVID-19 vaccination are documented, including ocular complications.
  • Literature increasingly reports ocular adverse events linked to COVID-19 vaccines.

Approach:

  • This systematic review compiles reported corneal-related effects of COVID-19 infection and vaccination.
  • It analyzes cases from global literature to identify trends and patterns.
  • The focus is on understanding the presentations, pathogenesis, and management strategies.

Key Points:

  • COVID-19 infection and vaccination can lead to direct effects on corneal grafts.
  • Unilateral or bilateral corneal melts are reported ocular complications.
  • The review aims to provide a comprehensive overview of these corneal issues.

Conclusions:

  • Clinicians can better recognize and manage COVID-19-related corneal complications.
  • Understanding the pathogenesis is crucial for effective treatment strategies.
  • This compilation aids in managing ocular side effects of COVID-19 and its vaccines.

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