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CHANGES IN MALE REPRODUCTIVE HORMONES IN PATIENTS WITH COVID-19
M Jabbar1, M Mohammad2, A Tiryag3
11College of Nursing, University of Basrah, Iraq.
Georgian Medical News
|November 22, 2023
Summary
COVID-19 significantly impacts male reproductive health, lowering testosterone and altering testosterone/luteinizing hormone (LH) ratios. These hormonal changes correlate with COVID-19 disease severity, affecting overall male fertility.
Area of Science:
- Endocrinology
- Virology
- Reproductive Medicine
Background:
- COVID-19 (caused by SARS-CoV-2) is primarily a respiratory illness but can cause extrapulmonary manifestations.
- Potential effects of COVID-19 on male reproductive hormones remain an area requiring further investigation.
Purpose of the Study:
- To investigate the impact of COVID-19 on male reproductive hormones, specifically testosterone and luteinizing hormone (LH).
- To determine if any observed hormonal changes are associated with COVID-19 disease severity.
Main Methods:
- A prospective case-control study involving 120 male COVID-19 patients (mild, moderate, severe) and 120 age-matched controls.
- Comparison of serum hormone profiles, including total testosterone, LH, and the testosterone/LH ratio between the groups.
Main Results:
- COVID-19 patients exhibited significantly lower total testosterone levels (P=0.043) compared to controls.
- Significantly higher serum LH levels (P=0.0001) and a lower testosterone/LH ratio (P=0.0001) were observed in COVID-19 patients.
- Hormonal alterations appeared to correlate with disease severity.
Conclusions:
- COVID-19 affects male reproductive hormones, including total testosterone, LH, and the testosterone/LH ratio.
- These hormonal changes may be linked to the severity of the COVID-19 infection.
- Further research is recommended to fully understand the long-term implications of COVID-19 on male reproductive health.
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