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Updated: Jul 10, 2025

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Rate of Pathogenic Germline Variants in Patients With Lung Cancer

Steven Sorscher1, Jaclyn LoPiccolo2, Brandie Heald1

  • 1Invitae, San Francisco, CA.

JCO Precision Oncology
|November 22, 2023
PubMed
Summary

Germline genetic testing in lung cancer (LC) patients reveals a high frequency of pathogenic germline variants (PGVs), particularly in DNA damage repair genes. These findings support broader GGT recommendations for lung cancer.

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Overview
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