Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Papillary Dermis01:11

Papillary Dermis

2.9K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
2.9K
Reticular Dermis01:15

Reticular Dermis

2.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
2.6K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Pigmentation01:19

Pigmentation

2.4K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ten specific updates for the Mexican atopic dermatitis guidelines, GUIDAMEX 1.1.

Boletin medico del Hospital Infantil de Mexico·2026
Same author

Ancestry and somatic profile indicate acral melanoma origin and prognosis.

Nature·2026
Same author

Clinicopathological Challenge: A Progressively Enlarging Hardened Skin Plaque.

International journal of dermatology·2025
Same author

Periungual squamous cell carcinoma in childhood: a case report.

Oxford medical case reports·2025
Same author

[Characteristics of melanoma in Mexicans seen at "La Raza" National Medical Center].

Revista medica del Instituto Mexicano del Seguro Social·2024
Same author

Ancestry and somatic profile predict acral melanoma origin and prognosis.

medRxiv : the preprint server for health sciences·2024

Related Experiment Video

Updated: Jul 10, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

88

Dermatoscopic Patterns in Vitiligo.

Juan Alberto Godínez-Chaparro1,2, Rodrigo Roldán-Marín3, Helena Vidaurri-de la Cruz4

  • 1Pediatric Dermatology Service, High Specialty Medical Unit of the Dr. Gaudencio González Garza General Hospital, La Raza National Medical Center, Mexican Social Security Institute, Mexico City, Mexico.

Dermatology Practical & Conceptual
|November 22, 2023
PubMed
Summary

Dermoscopy aids in diagnosing vitiligo, assessing disease activity, and predicting treatment response by visualizing subtle pigmentary changes. Key indicators include perifollicular patterns and lesion border characteristics.

More Related Videos

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

930
The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
11:02

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression

Published on: August 3, 2011

49.7K

Related Experiment Videos

Last Updated: Jul 10, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

88
Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

930
The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
11:02

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression

Published on: August 3, 2011

49.7K

Area of Science:

  • Dermatology
  • Medical Diagnostics

Background:

  • Vitiligo is a chronic autoimmune skin condition affecting pigmentation.
  • Clinical diagnosis is common, but dermoscopy offers non-invasive confirmation.
  • Dermoscopy reveals sub-macroscopic structures correlating with histology.

Purpose of the Study:

  • To detail the diagnostic and prognostic utility of dermoscopy in vitiligo.
  • To describe specific dermatoscopic clues for assessing vitiligo activity and treatment response.
  • To differentiate vitiligo from other hypopigmentary disorders using dermoscopy.

Main Methods:

  • Dermoscopic examination of vitiligo lesions.
  • Analysis of morphological structures and pigment patterns.
  • Correlation of dermatoscopic findings with disease activity and treatment outcomes.

Main Results:

  • Dermoscopy evaluates pigment patterns, activity, re-pigmentation attempts, and leucotrichia.
  • Perifollicular clues (pigmentation/depigmentation) indicate activity and prognosis.
  • Lesion center and periphery characteristics (e.g., pigment network, border patterns) are crucial for assessment.

Conclusions:

  • Dermoscopy is a valuable tool for comprehensive vitiligo assessment.
  • Specific dermatoscopic features predict treatment response and disease stability.
  • It aids in differentiating vitiligo from other pigmentary disorders.