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Updated: Jul 10, 2025
Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
Published on: November 28, 2015
The missing link? LGMN connects hypoxia and immunosuppression in glioblastoma
Jonathan Mitchell1, Bruno Colon1, Defne Bayik2
1Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL, USA.
Abstract:
In this issue, Pang and colleagues1 identify the protease legumain as a potential immunotherapy target in glioblastoma that drives tumor-associated macrophages in response to hypoxia.
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