Related Experiment Video
Updated: Jul 10, 2025
10:27
Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion
Published on: December 10, 2020
3.5K
Time Dependent Correlation Between Sac Behaviour and Re-intervention after Endovascular Aneurysm Repair
Ioanna E Kyrou1, Constantine N Antonopoulos2, George A Antoniou3
1Department of Vascular and Endovascular Surgery, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Summary
Aneurysm sac regression after endovascular aneurysm repair (EVAR) is linked to a longer time before re-intervention. Stable or expanding sacs indicate a higher risk of needing re-intervention sooner.
Area of Science:
- Vascular Surgery
- Medical Imaging
- Biostatistics
Background:
- Endovascular aneurysm repair (EVAR) is a common treatment for abdominal aortic aneurysms.
- Monitoring aneurysm sac behavior post-EVAR is crucial for predicting outcomes.
- Understanding factors influencing re-intervention is vital for optimizing patient management.
Purpose of the Study:
- To determine the relationship between abdominal aortic aneurysm sac behavior and the time to re-intervention after EVAR.
- To identify specific sac behaviors that predict the need for subsequent procedures.
Main Methods:
- Retrospective observational cohort study of patients undergoing EVAR.
- Stratification into sac regression, stable sac, and sac expansion groups based on imaging.
- Cox proportional hazards model used to analyze re-intervention free time.
Main Results:
- Patients with sac regression showed significantly higher freedom from re-intervention (94% at 12 years) compared to stable (57%) or expanding sacs (16%).
- Mean time to re-intervention was longest for sac regression (11.3 years) and shortest for sac expansion (5.0 years).
- Risk of re-intervention increased sharply at 6 years for stable sacs and 3.5 years for expanding sacs.
Conclusions:
- Aneurysm sac behavior is a significant time-dependent predictor of re-intervention after EVAR.
- These findings support tailored surveillance strategies based on post-EVAR sac dynamics.
- Monitoring sac behavior can help anticipate the need for re-intervention and guide clinical decisions.
