Is there a significant difference in the oral microbiome in vapers vs non-vapers?

This study was a secondary data analysis of a parent study that was initially designed to assess saliva and exhaled breath for passive e-cigarette vapour exposure in children. The initial study collected patients using convenience sampling of the local community between July 2018 and February 2019 and ethical approval was obtained prior to commencing.

Eligibility criteria for the parent vapers in the original study included self-reported daily use of e-cigarettes in the presence of children via the use of a questionnaire. Microbiome data for a total of 36 adults were collected and analysed in this study (18 vapers and 18 non-vapers).

Vapers have a distinct oral microbiome compared with non-vapers. They tend to have a higher relative abundance of Veilonella, an opportunistic pathogen that can stimulate the growth of other opportunistic pathogens. This species has also been found in carious lesions compared with healthy tooth surface.