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[Research progress on genetic variants of PDE4D and susceptibility to stroke in Chinese population]

Guiying Zhang1, Xinrui Yu, Xuelei Tang

  • 1Department of Biology, Hainan Medical University, Haikou, Hainan 571199, China. xianronglin@gmail.com.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics
|November 23, 2023
PubMed

Insights

Genetic variants in phosphodiesterase 4D (PDE4D) are linked to ischemic stroke (IS) risk in Caucasians. This review examines PDE4D

Area of Science:

  • Neuroscience
  • Genetics
  • Epidemiology

Background:

  • Stroke pathogenesis involves complex genetic factors.
  • Phosphodiesterase 4D (PDE4D) gene variants are linked to ischemic stroke (IS) susceptibility in Caucasian populations.
  • The association between PDE4D genetic variants and stroke risk in the Chinese population remains unclear.

Conclusions:

  • The role of PDE4D genetic variants in stroke susceptibility among the Chinese population requires more extensive research.
  • Clarifying these associations can inform targeted prevention and treatment strategies.
  • Optimized research programs are crucial for advancing stroke care in China.

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