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Updated: Jul 10, 2025

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Feedback control in hemodialysis
Ashveer Randhay1,2, Mohamed Tarek Eldehni1,2, Nicholas M Selby1,2
1Centre for Kidney Research and Innovation, School of Medicine, University of Nottingham, Nottingham, UK.
Abstract:
A number of systems of feedback control during dialysis have been developed, which have the shared characteristic of prospectively measuring physiological parameters and then automatically altering dialysis parameters in real time according to a pre-specified dialysis prescription. These include feedback systems aimed at reducing intradialytic hypotension based on relative blood volume monitoring linked to adjustments in ultrafiltration and dialysate conductivity, and blood temperature monitoring linked to alterations in dialysate temperature. Feedback systems also exist that manipulate sodium balance during dialysis by assessing and adjusting dialysate conductivity. In this review article, we discuss the rationale for automated feedback systems during dialysis, describe how the different feedback systems work, and provide a review of the current evidence on their clinical effectiveness.
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