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Updated: Jul 10, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Access to a Diverse Array of Bridged Benzo[1,5]oxazocine and Benzo[1,4]diazepine Structures

Grant J Sherborne1, Coura Diène1, Paul Kemmitt1

  • 1Medicinal Chemistry Oncology R&D, Research and Early Development, AstraZeneca, The Discovery Centre, Cambridge Biomedical Campus, 1 Francis Crick Avenue, Cambridge CB2 0AA, U.K.

Organic Letters
|November 23, 2023
PubMed

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