Anthropometric measurements and body composition of preterm infants born ≤34 weeks at 12-13 months corrected age as

Apoorva Kutar1, Padmasani Venkat Ramanan1, Kandathil Eapen Elizabeth2

  • 1Department of Pediatrics, Sri Ramachandra Institute of Higher Education and Research, No. 1, Ramachandra Nagar, Porur, Chennai, Tamil Nadu 600116, India.

PubMed

Insights

Preterm infants born before 34 weeks gestation show significantly lower growth and body composition at 12-13 months corrected age compared to term infants. These preterm infants did not achieve catch-up growth within the first year.

Area of Science:

  • Neonatal research
  • Pediatric nutrition
  • Growth and development studies

Background:

  • Infant growth in the first year is nutrition-dependent.
  • Current infant feeding practices for preterm infants are extrapolated from term infants.
  • The use of corrected age (CA) versus chronological age for preterm infants is unclear, especially for those born ≤34 weeks gestation.

Purpose of the Study:

  • To compare growth parameters and body composition of preterm infants (born ≤34 weeks gestation) with term infants at 12-13 months corrected age (CA).
  • To evaluate if preterm infants achieve catch-up growth within the first year when assessed by CA.

Main Methods:

  • Evaluated growth of 99 term infants and 170 preterm infants (born ≤34 weeks gestation) at 12-13 months CA.
  • Measured anthropometric parameters, including body mass index (BMI) and skin fold thickness (SFT) at four sites.
  • Used the sum of SFT as a marker for fat mass.

Main Results:

  • Preterm infants had significantly lower weight, length, and BMI at 12-13 months CA compared to term infants.
  • Weight-for-age Z-scores, BMI-for-age Z-scores, weight-for-length Z-scores, and fat mass were significantly reduced in preterm infants.
  • Preterm infants did not demonstrate catch-up growth by 12-13 months CA, even when using corrected age.

Conclusions:

  • Anthropometric measurements in preterm infants (born <34 weeks) at 12-13 months CA were significantly lower than in term infants.
  • The study suggests that preterm infants in this cohort did not achieve catch-up growth within the first year, even when using corrected age.
  • The multifactorial causes for the observed growth deficits require further investigation.
Abstract