Related Experiment Video
Updated: Jul 10, 2025
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Group A Streptococcus invasive infection in children: Epidemiologic changes and implications
J T Ramos Amador1, A Berzosa Sánchez, M Illán Ramos
1José Tomás Ramos Amador, Department of Pediatrics, Hospital Clínico San Carlos, Madrid, Spain. josetora@ucm.es.
Group A Streptococcus (GAS) infections are rising in children post-pandemic. This increase is linked to reduced immunity from COVID-19 isolation, not new strains, necessitating prompt treatment and surveillance.
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology
- Microbiology
Background:
- Group A Streptococcus (GAS) causes diverse clinical issues.
- Recent months show increased pediatric invasive GAS infections in Europe.
- This rise follows COVID-19 pandemic isolation measures.
Purpose of the Study:
- To analyze the recent surge in invasive Group A Streptococcus infections in children.
- To investigate the contributing factors behind the increased incidence and severity.
- To highlight the need for enhanced surveillance and early intervention.
Main Methods:
- Observational analysis of pediatric invasive GAS cases.
- Correlation with seasonal viral respiratory pathogen incidence.
- Assessment of potential contributing factors like immunity gaps.
Main Results:
- Increased incidence and severity of invasive GAS infections observed in young children.
- No specific predominant GAS strains identified as the cause.
- Reduced population immunity to GAS and viral infections linked to COVID-19 isolation is a likely factor.
Conclusions:
- Prompt medical and surgical treatment is crucial due to nonspecific initial symptoms.
- Prevention strategies and continuous microbiological surveillance of invasive GAS strains are essential.
- Addressing immunity gaps may be key to mitigating future outbreaks.
More Related Videos
11:32Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
09:25Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells
Published on: August 19, 2016
Related Concept Videos
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:30Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:20Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
01:26Stages of Infection