Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mania following head trauma.

S Shukla, B L Cook, S Mukherjee

    The American Journal of Psychiatry
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Erratum to: Blueberry Supplementation Effects on Neuronal and Pathological Biomarkers in Subjects at Risk for Alzheimer's Disease: A Pilot Study.

    JAR life·2023
    Same author

    Blueberry Supplementation Effects on Neuronal and Pathological Biomarkers in Subjects at Risk for Alzheimer's Disease: A Pilot Study.

    JAR life·2023
    Same author

    Dietary strawberry improves cognition in a randomised, double-blind, placebo-controlled trial in older adults - ERRATUM.

    The British journal of nutrition·2021
    Same author

    Ventilation rates in recently constructed U.S. school classrooms.

    Indoor air·2017
    Same author

    Mental health, migration stressors and suicidal ideation among Latino immigrants in Spain and the United States.

    European psychiatry : the journal of the Association of European Psychiatrists·2016
    Same author

    Air exchange rates and migration of VOCs in basements and residences.

    Indoor air·2015
    Same journal

    2026 Annual Meeting: President-Elect Address.

    The American journal of psychiatry·2026
    Same journal

    2026 Annual Meeting: CEO and Medical Director's Address.

    The American journal of psychiatry·2026
    Same journal

    Reports to the Membership.

    The American journal of psychiatry·2026
    Same journal

    Convergent Metabolic Dysregulations But Divergent Contributing Pathways Across Severe Mental Disorders: The Power of Combining Genetics and Metabolomics.

    The American journal of psychiatry·2026
    Same journal

    2026 Annual Meeting: Presidential Address.

    The American journal of psychiatry·2026
    Same journal

    Represcribing Previously Used Antipsychotics: Response to So.

    The American journal of psychiatry·2026
    See all related articles

    Closed head trauma can lead to mania, particularly with severe injuries and posttraumatic seizures. These manic episodes often feature irritability and assaultiveness, suggesting seizures may predispose individuals to this condition.

    Area of Science:

    • Neurology
    • Psychiatry
    • Trauma Studies

    Background:

    • Head trauma is a significant cause of neurological and psychiatric morbidity.
    • Understanding the specific psychiatric sequelae of head injuries is crucial for patient management.

    Purpose of the Study:

    • To investigate the characteristics of mania following closed head trauma.
    • To explore potential associations between head trauma severity, seizures, and bipolar disorder presentation.

    Main Methods:

    • Retrospective analysis of psychiatric and neurologic data from 20 patients with mania post-head trauma.
    • Assessment of head trauma severity using posttraumatic amnesia duration.
    • Evaluation of seizure disorder and bipolar disorder type.

    Related Experiment Videos

    Main Results:

    • An association was observed between head trauma severity, posttraumatic seizure disorder, and bipolar disorder type.
    • Manic episodes were predominantly characterized by irritability and assaultiveness, not euphoria.
    • Psychosis was present in 15% of patients; 70% did not experience depressive episodes.
    • No history of bipolar disorder was found in 85% of first-degree relatives.

    Conclusions:

    • Posttraumatic seizures may act as a predisposing factor for developing mania after head trauma.
    • The presentation of posttraumatic mania differs from typical bipolar disorder, with less euphoria and fewer depressive episodes.
    • Severity of head injury correlates with the development of posttraumatic mania.