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Updated: Jul 10, 2025

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Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
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Protocol to fabricate wearable stretchable microneedle-based sensors.
Rawan Omar1, Youbin Zheng2, Hossam Haick1
1Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
STAR Protocols
|November 24, 2023
Summary
Researchers developed a stable, conductive, and flexible microneedle sensor patch. This innovation addresses challenges in combining elastic and rigid materials for advanced wearable electronics.
Area of Science:
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- Developing stretchable and robust electrodes with stable conductivity is difficult.
- Integrating flexible and rigid components in devices poses material compatibility challenges.
Purpose of the Study:
- To present a protocol for creating a stable, conductive, and flexible microneedle sensor patch.
- To overcome the material discrepancies between elastic and rigid components in wearable sensors.
Main Methods:
- Utilizing polystyrene-block-polyisoprene-block-polystyrene (PIPS) with silver nanowires.
- Fabricating rigid microneedles.
- Employing a thickness-gradient strategy for seamless integration of flexible and rigid parts.
Main Results:
- A protocol for a stable, conductive, and flexible microneedle sensor patch was successfully developed.
- The method enables the combination of dissimilar material properties for integrated devices.
Conclusions:
- The presented protocol offers a viable solution for creating advanced microneedle sensor patches.
- This work contributes to the field of flexible and wearable electronics by enabling robust material integration.

