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Promoting data harmonization to evaluate vaccine hesitancy in LMICs: approach and applications
Ryan T Rego1,2, Yuri Zhukov3,4, Kyrani A Reneau5
1Center for Global Health Equity, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. ryanregoph@gmail.com.
BMC Medical Research Methodology
|November 24, 2023
Summary
Integrating diverse datasets is crucial for public health research. A new toolkit, SUNGEO, links health data with factors like political violence, revealing vaccine hesitancy correlates with instability and poor access to public goods.
Area of Science:
- Public Health
- Geospatial Analysis
- Computational Social Science
Background:
- Public health research requires interdisciplinary data, but combining datasets is challenging due to geographic, structural, and methodological incompatibilities.
- Existing datasets often lack the breadth to link health outcomes with crucial contextual factors like political violence or development.
Purpose of the Study:
- To present a computational package, Sub-National Geospatial Data Archive (SUNGEO), for combining spatially misaligned and incompatible datasets.
- To demonstrate the utility of SUNGEO by analyzing multi-dimensional factors influencing vaccine hesitancy in Low and Middle-Income Countries (LMICs).
Main Methods:
- Utilized SUNGEO to integrate World Bank High Frequency Phone Surveys (HFPS) from Kenya, Indonesia, and Malawi with data on political violence, elections, and economic development.
- Developed a stochastic model to assess the stability of vaccination preferences and their association with local contextual factors.
Main Results:
- Vaccine acceptance was more persistent than hesitancy across all countries.
- Vaccine acceptance durability significantly decreased in areas with political violence (-10% to -64% ppd).
- Vaccine acceptance was less durable in locations lacking competitive elections and with limited transportation infrastructure in Indonesia and Kenya.
Conclusions:
- SUNGEO enables the integration of disparate datasets for comprehensive public health analysis.
- Vaccine hesitancy is correlated with political violence, electoral uncompetitiveness, and limited public goods access, suggesting links to government distrust.
