[Branched-chain amino acids: indicators of fetal nutritional status]

Both nutritive state for Rohrer's ratio (Rr) and serum aminoacids (aa) (Chromatospek J-180) of the umbilical cord have been analyzed and correlated in two groups of the newborns: G-I (n: 12) preterm infants with an adequated weight for their gestational age (Re greater than 10 percentile) and G-II (n: 8) small for-date term infants (Rr less than 10 p). Ratios of the serum aa (total aa, no essential aa, NE/E, Ala/Thr, Whitehead's ratio (Wr), Ala/Leu, Ala/BCA, Gly/Val, Ser + Gly + Ala/BCA) were more elevated in G-II than those one of the G-I. We have shown a single correlation between Wr and Rr (r. much greater than 0.48, p less than 0.025) in G-I and between BCA Rr (r. much greater than 0.88, p less than 0.0025) in G-II; furthermore, we have proved a good correlation between the week of gestation and sum of BCA (r. much greater than 0.53, p less than 0.05) in the former that have not been observed among the latter which had BCA more increased than G-I (p less than 0.050). Some speculations about the role that could play the BCA in the energetic metabolism of the small-for-date infants are made; on the other hand, the BCA can give help to distinguish between premature or pseudopremature among infants weighing 2.500 g or less a birth.