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Sophisticated Study of Time, Frequency and Statistical Analysis for Gradient-Switching-Induced Potentials during MRI.

Karim Bouzrara1,2, Odette Fokapu3,4, Ahmed Fakhfakh1,5

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Summary

Magnetic resonance imaging (MRI) gradient switching creates voltage artifacts that interfere with electrophysiological signals (EPs). Understanding these MRI artifacts is key to developing digital tools for cleaner EPs.

Keywords:
KPSS testMRIbiomedical engineeringimage and signal processinginduced potentialsmedical image analysis and medical decision-makingstationarity testsurrogatestime and frequency analysis

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Area of Science:

  • Biomedical Engineering
  • Medical Imaging Physics

Background:

  • Magnetic resonance imaging (MRI) is a non-ionizing medical imaging technique that produces high-resolution images.
  • Electrophysiological signals (EPs) are susceptible to interference from induced voltages generated by MRI's magnetic field gradients.
  • High-bandwidth amplifiers (>150 Hz) struggle to eliminate these induced voltages, impacting signal quality.

Purpose of the Study:

  • To investigate the characteristics of induced voltages generated during MRI acquisition.
  • To analyze the behavior of these artifacts to inform the development of signal processing tools.
  • To assess the stationarity of induced potentials at different analysis scales.

Main Methods:

  • In vitro study of induced voltages using a 350 Hz bandwidth device on a 1.5T MRI scanner.
  • Utilized two MRI sequences (fast spin echo and cine gradient echo) and three slice orientations.
  • Analyzed recorded voltages using global and local approaches, including stationarity tests (KPSS) and time-frequency analysis.

Main Results:

  • Induced voltage characteristics (temporal, frequency) were specific to MRI sequences and slice orientations.
  • Significant variability was observed within recordings, despite the pseudo-periodic nature of artifacts.
  • Induced potentials were stationary globally but non-stationary locally, especially within the 0-500 Hz bandwidth.

Conclusions:

  • The non-stationarity of MRI-induced artifacts at a local scale presents challenges for designing effective filters.
  • Understanding artifact behavior is crucial for developing advanced digital processing to reduce interference in EPs.
  • This research contributes to improving the quality of electrophysiological data acquired concurrently with MRI.