Related Experiment Video
Updated: Jul 10, 2025
Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Ischemic Stroke in the Course of COVID-19 in a 16-Year-Old Boy
Bartłomiej Syzdoł1, Anna Maria Rzewuska1, Wiktoria Sielwanowska1
1Students' Scientific Society at the Department of Pediatric Radiology, Medical University of Lublin, 20-059 Lublin, Poland.
Insights
Multisystem inflammatory syndrome in children (MISC) is a rare complication of SARS-CoV-2 infection. This case highlights a MISC patient who developed an ischemic stroke, emphasizing the need for vigilance in pediatric cases.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- The SARS-CoV-2 virus continues to evolve, posing ongoing public health risks.
- Multisystem inflammatory syndrome in children (MISC) is a rare but serious complication of COVID-19, affecting less than 1% of pediatric cases.
- MISC carries risks of life-threatening thromboembolic and cardiac complications.
Observation:
- A 16-year-old boy presented with fever, conjunctivitis, gastrointestinal symptoms, and general weakness.
- The patient's mother had a positive SARS-CoV-2 test.
- During hospitalization, the patient developed neurological symptoms including dysarthria and right-sided weakness.
Findings:
- Laboratory tests and clinical presentation were consistent with MISC.
- Magnetic resonance imaging revealed changes indicative of an ischemic stroke.
- The patient received anticoagulant therapy, antipyretics, steroids, and IVIG.
Implications:
- This case underscores the potential for severe thrombotic complications, such as ischemic stroke, in children with MISC.
- Further research is necessary to understand and manage thrombotic risks associated with SARS-CoV-2 infection in pediatric populations.
- Healthcare providers should maintain heightened vigilance for neurological and thrombotic complications in children presenting with MISC symptoms.
Abstract:
The SARS-CoV-2 virus that causes COVID-19 disease is still evolving and, despite the end of the acute phase of the pandemic, still poses a risk to public health. One of the very rare complications, occurring in less than 1% of children, is multisystem inflammatory syndrome in children (MISC). Due to the risk of thromboembolic complications as well as cardiac problems, MISC carries a number of life-threatening complications. We report a case of a 16-year-old boy who was hospitalized due to general weakness, fever, conjunctivitis, vomiting and diarrhoea. In view of the mother's positive result of the SARS-CoV-2 test, the teenager underwent numerous laboratory tests. Taking into account the critical condition of the patient, anticoagulant and antipyretic treatment, steroids and IVIG were added. During hospitalisation, alarming symptoms occurred, including dysarthria, drooping corner of the mouth and muscle weakness on the right side. The magnetic resonance imaging showed changes characteristic of ischemic stroke. Further studies are needed to assess possible thrombotic complications in children after SARS-CoV-2 infection, and specialists should be more vigilant in paediatric patients presenting with such symptoms.
More Related Videos
Related Concept Videos
01:17Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
01:27Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...